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IIizarov Correction of Malrotated Femoral Shaft Fracture Initially Treated With an Intramedullary Nail: A Case Report

Thu, 08 Oct 2026 18:10:59 GMT

Source: The American Journal of Orthopedics

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IIizarov Correction of Malrotated Femoral Shaft Fracture Initially Treated With an Intramedullary Nail.pdf 71.546 KB

The American Journal of Orthopedics

Mark R. Brinker,MD,Joseph J. Gugenheim, MD, Daniel P. O'Connor, PhD,

and Jeffrey c. London,. MD

IIizarov Correction of Malrotated Femoral Shaft Fracture Initially Treated With an Intramedullary Nail: A Case Report

CT Scan Helps Delineate Cervical Osteoid Osteoma and Atypical Nidus

Thu, 08 Oct 2026 18:10:58 GMT

CT Scan Helps Delineate Cervical Osteoid Osteoma and Atypical Nidus

The Journal of Bone and Joint Surgery

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CT Scan Helps Delineate Cervical Osteoid Osteoma And Atypical Nidus.pdf 45.433 KB

Source: The Journal of Bone and Joint Surgery

Click here to read the entire published article by Dr. Brinker

Robert L. Barrack, MD, Mark R. Brinker, BA, Stephen W. Burke, MD; and John M. Roberts, MD

Nonunions of the Femoral Shaft and Distal Femur

Thu, 08 Oct 2026 18:10:57 GMT

Nonunions of the Femoral Shaft and Distal Femur

Rozbruch, Vol. 11

Source: Rozbruch

Author: Mark R. Brinker,MD and Daniel P. O'Connor

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Brinker_Rozbruch_Ch11_R1 Proofs.pdf 3823.33 KB

Payer Type Has Little Effect on Operative Rate and Surgeons’ Work Intensity

Thu, 08 Oct 2026 18:10:56 GMT

Payer Type Has Little Effect on Operative Rate and Surgeons’ Work Intensity

Author: Mark R. Brinker,MD, Daniel P. O'Connor,PhD, Peggy Pierce,FACMPE and James Weston Spears,BCE

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Clinical Orthopaedics and Related Research, No. 451, pp.257-262 Oct 2006

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Payer Type CORR 2006.pdf 119.538 KB

Source: Clinical Orthopaedics and Related Research, No. 451, pp.257-262 Oct 2006

Ilizarov Treatment of Infected Nonunions of the Distal Humerus After Failure of Internal Fixation: An Outcomes Study

Thu, 08 Oct 2026 18:10:55 GMT

Source: J Orthop Trauma ,Vol. 21, Number 3, March 2007

J Orthop Trauma ,Vol. 21, Number 3, March 2007

Author: Mark R. Brinker,MD, Daniel P. O'Connor,PhD, C. Craig Crouch,MD, Thomas L. Mehlhoff,MD, and James B. Bennett,MD

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Ilizarov Treatment of Infected Nonunions of the Distal Humerus After Failure of Internal Fixation: An Outcomes Study

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Iliz Infected Distal Hum JOT 2007.pdf 276.368 KB

Metabolic and Endocrine Abnormalities in Patients With Nonunions

Thu, 08 Oct 2026 18:10:53 GMT

Objectives: To determine whether patients with unexplained nonunions, patients with a history of multiple low-energy fractures with at least one progressing to a nonunion, and patients with a nonunion of a nondisplaced pubic rami or sacral ala fracture would have an underlying metabolic or endocrine abnormality that had not been previously diagnosed.

Design: Case series.

Setting: Tertiary referral center. Patients and Intervention: From a larger series of 683 consecutive patients with nonunion seen by us between January 1998 and December 2005, 37 patients were referred to 1 of 2 clinically practicing endocrinologists to undergo an evaluation for metabolic and endocrine abnormalities. The screening criteriawere: 1) an unexplained nonunion that occurred despite adequate reduction and stabilization (and debridement in initially infected cases) without obvious technical error and without any other obvious etiology; 2) a history of multiple low-energy fractures with at least one progressing to a nonunion; or 3) a nonunion of a nondisplaced pubic rami or sacral ala fracture.

Results: In all, 31 of the 37 patients (83.8%, 95% CI: 71.3% to 93.8%) who met our screening criteria had one or more new diagnoses of metabolic or endocrine abnormalities. The most common newly diagnosed abnormality was vitamin D deficiency (25 of 37 patients; 68%). Other newly diagnosed abnormalities included calcium imbalances, central hypogonadism, thyroid disorders, and parathyroid hormone disorders. All newly diagnosed abnormalities were treated medically. Eight patients who underwent no operative intervention following the diagnosis and treatment of a new metabolic or endocrine abnormality achieved bony union in an average of 7.6 months (range, 3 to 12 months) following their first visit to the endocrinologist.

Conclusions: Although our study does not prove a causal link between metabolic and endocrine abnormalities and either the development or healing of nonunions, 84% of the patients who met our screening criteria were found to have metabolic or endocrine abnormalities, and eight of our patients achieved bony union following medical treatment alone. All patients with nonunion who meet our screening criteria should be referred to an endocrinologist for evaluation because they are likely to have undiagnosed metabolic or endocrine abnormalities that may be interfering with bone healing.

KeyWords: fractures, ununited, bone, hormone, calcium, vitamin D, hypogonadism

Source: J Orthop Trauma, Vol 21, No.8, Sept 2007

J Orthop Trauma, Vol 21, No.8, Sept 2007

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Brinker Metab endoc abnl NU J Orthop Trauma 2007.pdf 277.16 KB

Author: Mark R. Brinker, MD, Daniel P. O'Connor, PhD, Yomna T. Monla, MD, and Thomas P. Earthman, MD

Metabolic and Endocrine Abnormalities in Patients With Nonunions

Outcomes of Tibial Nonunion in Older Adults Following Treatment Using the Ilizarov Method

Thu, 08 Oct 2026 18:10:51 GMT

Outcomes of Tibial Nonunion in Older Adults Following Treatment Using the Ilizarov Method

J Orthop Trauma, Vol. 2, No. 9, October 2007

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Tib NU Older Adults J Orthop Trauma 2007.pdf 499.379 KB

Objectives: To describe the functional outcomes of treatment using the Ilizarov method for tibial nonunions in older patients (.60 years of age).

Design: Prospective case series. Setting: Tertiary referral center.

Patients: Twenty-three consecutive patients with an average age of 72 years (61 to 92) who had tibial nonunions for an average duration of 13 months (3 to 46). Fourteen patients had an associated deformity and eight patients had infection.

Intervention: Ilizarov deformity correction, compression, or bone transport.

Main Outcome Measurements: Brief Pain Inventory, American Academy of Orthopaedic Surgeons (AAOS) Lower Limb Core Scale, Short Form (SF)-12, quality-adjusted life years.

Results: Three patients did not complete treatment: two patients died of cardiovascular disease during the treatment period and one patient demanded early removal of the Ilizarov device against medical advice. All 20 patients who completed treatment achieved bony union. Two of the 20 patients died before final follow-up, one patient was unable to participate in follow-up, and one patient was lost. At an average follow-up of 38 months (18 to 61), all of the remaining 16 patients were bearing full weight. AAOS Lower Limb Core Scale scores improved from 39 to 78 points (P , 0.001), pain intensity decreased from 3.6 to 0.9 (P = 0.001), SF-12 Physical Component Summary scores improved from 26.5 points to 35.3 points (P = 0.030), and SF-12 Mental Component Summary scores improved from 41.6 points to 48.7 points (P = 0.011). The improvement in quality of life is equivalent to 5.3 quality-adjusted life years per patient, which was larger than the average improvement in quality of life following total hip arthroplasty reported in published series.

Conclusions: Treatment using the Ilizarov method restored function and had a profoundly positive effect on quality of life in these elderly patients with tibial nonunions.

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Source: Journal of Orthopaedic Trauma

Author: M.R. Brinker, MD and Daniel P.O O'Conner, PhD

Ilizarov Distraction Before Revision Hip Arthroplasty After Resection Arthroplasty With Profound Limb Shortening

Thu, 08 Oct 2026 18:10:50 GMT

Author: Mark R. Brinker, MD, Daniel P. O'Connor, PhD, Vasilios Mathews, MD

The Journal of Arthroplasty Vol. 00 No. 0 2008

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Source: The Journal of Arthroplasty Vol. 00 No. 0 2008

Ilizarov Distraction Before Revision Hip Arthroplasty After Resection Arthroplasty With Profound Limb Shortening

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Brinker_2008_The-Journal-of-Arthroplasty.pdf

Management of Falls After Total Knee Arthroplasty

Thu, 08 Oct 2026 18:10:50 GMT

Author: Richard J. Kearns,MD, Mark R. Brinker,MD and Daniel P. O'Connor, PhD

Orthopedics, Vol 31, No.3, March 2008

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Brinker Calcaneogenesis JBJS Br 2009.pdf

This study evaluated 78 patients who fell after total knee arthroplasty. Eight patients (10.3%) had soft-tissue injuries that led to a poor clinical course (deep infection, unplanned return to the operating room, temporary or permanent resection arthroplasty, or knee arthrodesis).

Factors related to a poor clinical course included copious bleeding from the surgical wound immediately after falling, falling within 8 weeks of arthroplasty, and rupturing the parapatellar surgical wound and quadriceps repair. Patients who fall and have bleeding from their surgical wound should receive emergency surgical irrigation and debridement. A treatment protocol for patients who fall after total knee arthroplasty is presented.

Source: Orthopedics, Vol 31, No.3, March 2008

Click here to read the entire published article by Dr Brinker